Material Adverse Change (MAC)


The Empire BlueCross BlueShield (Empire) pre-service clinical review of non-oncology specialty pharmacy drugs will be managed by Empire’s Medical Specialty Drug Review team. Oncology drugs will be managed by AIM Specialty Health® (AIM),* a separate company.


The following clinical criteria document was endorsed at the April 19, 2022, Clinical Criteria meeting. To access the clinical criteria information, please select here.


New clinical criteria effective September 1, 2022

The following clinical criteria is new:

  • ING-CC-0200 Aduhelm (aducanumab-avwa)


*AIM Specialty Health is an independent company providing some utilization review services on behalf of Empire BlueCross BlueShield




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July 2022 Newsletter